Vivostat PRF® (Platelet Rich Fibrin)
Platelets and growth factors have been used for many years to help regenerate tissue and stimulate bone formation in e.g. for chronic wounds and orthopaedic surgery.
The thrombocyte solution used in these cases has traditionally been supplied by the blood bank.
Recently, a number of commercial products have entered the market with simpler and smaller devices that are still based on the same centrifugation technology. Most products still require sterile handling and have shortcomings in both the biophysical properties and the delivery system.
Vivostat has solved these problems by leveraging the revolutionary technology used in the Vivostat® system for the preparation and application of autologous fibrin sealant. By combining a fibrin sealant solution with a platelet concentrate, it is possible to have a carrier, a controlled release and a medium for vascular ingrowth - all in one product, Vivostat PRF® (Platelet Rich Fibrin).
Using the Vivostat® system, you can prepare autologous platelets with multiple growth factors embedded in a fibrin sealant matrix. From 120 ml blood, 5-6 ml of Platelet Rich Fibrin (PRF®) is prepared.
Compared to conventional PRP products, Vivostat PRF® has a number of advantages:
- Combining the benefits of platelets and fibrin. With an average 7-fold increase over baseline blood levels, the platelet concentration in Vivostat PRF® exceeds the baseline platelet count of 1 million/μL, which has become a benchmark within platelet therapy. The fibrin matrix ensures a slow release of growth factors over time and effectively protects the growth factors against proteolytic degradation.
- Superior application performance. The specially designed Vivostat® Spraypen® and the unique combination of platelets and fibrin ensures easy, accurate and efficient application of Vivostat PRF®. Due to instant polymerisation and excellent adhesive properties of the fibrin component, the PRF® solution remains where it is applied - even when applied on vertical or inverted surfaces. As the fibrin component in Vivostat PRF® is based on a fibrin 1 solution, there is no need to use a separate thrombin component.
Naturally utilising the combination of platelets and fibrin sealant has many more benefits.