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Vivostat Autologous Fibrin Sealant

Fibrin Set

Vivostat Autologous Fibrin Sealant


For many years specialists have prepared autologous fibrin sealant based on thrombin and fibrinogen, e.g. for achieving hemostasis and sealing of closed tissues to avoid leakage. The process is complicated, labour intensive and time consuming. With the Vivostat® system this process becomes fast and uncomplicated.

The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous fibrin sealant and related products without using cryoprecipitation and without the need for a separate thrombin component. Furthermore, Vivostat® Fibrin Sealant does not contain any bovine components and is completely aprotinin-free.

It is designed to provide the best possible solution for many different settings independent of whether it is used in the surgical area or centrally in e.g. the transfusion centre or the blood bank. The straightforward and intuitive operation means that there is no need for specially trained personnel.

The fully automated Vivostat® system prepares 5-6 ml of autologous fibrin sealant from 120 ml of the patient’s own blood in approx. 24 minutes.

Technical features

Compared to conventional sealant products, Vivostat® Fibrin Sealant offers a multitude of benefits to both the patient and the surgeon:

  • Excellent safety profile and high biocompatibility. Vivostat® Fibrin Sealant is derived from the patient’s own blood and as such it demonstrates excellent biocompatibility. Unlike conventional products, which are most often based on single donor blood, pooled blood or bovine components (e.g. aprotinin), Vivostat® Fibrin Sealant does not contain any exogenous thrombin or bovine components. The autologous nature of Vivostat® efficiently eliminates the risks of bovine or human borne contaminants. This is the only way to protect the patient against viral diseases not yet identified.
  • Unique and versatile application devices. The wide selection of application devices provide the surgeon with unparalleled freedom in the use of fibrin sealant throughout surgery. The application devices can be used intermittently during the entire surgical procedure without experiencing the blockage that is common in conventional systems. Furthermore, Vivostat® Fibrin Sealant can be applied at very close range allowing for pinpoint application, and rapid polymerisation ensures that the fibrin remains where it is applied.
  • Superior physical properties. Clinical studies and comparative tests have demonstrated that Vivostat® Fibrin Sealant is superior to conventional fibrin sealants on important parameters such as time to haemostasis, elasticity, adhesion to tissue and impact on tissue.

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